More current analyses do not show these risks to be associated (or present) with hormone therapy, including a follow-up study published in 2017. The study found that neither estrogen-plus-progestin taken for a median of 5.6 years, nor estrogen alone taken for a median of 7.2 years, was associated with increased risk of all-cause, cardiovascular or cancer mortality during a cumulative follow-up of 18 years. ( 7) Furthermore, the standard delivery of estradiol has changed from oral to transdermal, which was not previously studied by the WHI. free of estrogenics like 4-MBC, benzophenone, oxybenzone​, and other "-benz" and "-phen-" chemicals, free of titanium, etc.) Injectable Peptides: Legally, companies are required to say "research use only" for peptides. This makes people nervous but certain companies have sterling reputations and excellent purity. For BPC-157, TB-500, Epithalon, Fragment-176, Melanotan 2, and DSIP, my preferred company is Peptide Sciences, LINK Lithium: ConsumerLabs gave this supplement an excellent overall rating. Since I abhor anything with "orotate" (aka "orotic acid", which promotes liver cancer [ ref]) even if a tiny more might get into your brain with lithium orotate , this lithium aspartate is my favorite low-dose lithium supplement, Solaray, 5 mg, LINK CoQ10 Active Form Ubiquinol: This is another one that is difficult to get past your stomach acid and into your blood. The "QH" form appears to be excellent, though. Note, ubiquinol won't decrease iron uptake from your diet (like quercetin will) but it helps protect cells against damage from higher levels of iron. Jarrows Formulas, Ubiquinol QH-Absorb, LINK

First, think about your nerves. Nerves carry that lightning fast, electrical signaling; the speedy communication. Electrical hares. If you take any of the medications or supplements listed above under the vaginal ring, the patch may be less effective. Apparently—we were additionally informed during that memorable Ave orientation lecture— you shouldn’t drink the tap water because water in that Southernmost region of America contained especially high levels of birth-control hormones. EE2 it was called. Nobody really explained what EE2 did exactly or why chugging EE2 was bad but it sure sounded odious. Man boobs? suggested a classmate after the talk. When men don’t have enough estrogen, they can carry excess belly fat and experience low sexual desire. Taking Prescription Estrogen NusaPure, Licorice Extract, DGL (DGL means "DegGLycyrrhizinated" which is another way of saying the licorice sugars have been removed to prevent blood pressure issues. Note: removing these licorice sugars may or may not also remove phytoestrogens - no studies have been done so you'll need to test for yourself and let me know!], LINK andThe primary use of estrogen therapy lies in its treatment of menopausal symptoms. Although there is currently a reduction in estrogen therapy as a preventative treatment, it is still routinely used to treat menopausal symptoms locally. Typically, drugs administered vaginally are used mainly for their local effects, but they can also have systemic effects. Estrogen is a steroid hormone that plays a central role in the reproductive system by altering the transcription of genes in specific organs and tissues, primarily the uterus and vagina. The genes undergo alteration through the act of estrogen on certain receptors, known as nuclear transcription factors. Once bound by estrogen, these nuclear transcription factors are then able to bind to promoter regions in sequences of specific genes and are therefore able to regulate these genes. [3]Once these genes get transcribed, this allows for the development, regulation, and maintenance of the uterus and vagina. But, wait. Estrogen receptor? Let’s define estrogen receptor and look at the 80/20 Principle to understand how an estrogen receptor works. Overall, the report concluded that the study was “successful at reducing exposures to harmful chemicals in plastic” by promoting significant behavior change in participants. Further, the study was successful at promoting participants to spread the study messages in their communities. Lastly, the blood samples provided “very promising preliminary results that need further testing.”

Estrogen and estrogenics function within the steroid hormone system. I parallel this steroid hormone system to a radio broadcasting system. The good news is that by the time you finish this book, you will have a thorough grasp on the sources of artificial estrogen in your environment and you will know how to remove them like a pro. It will change your life, your view of reality, and, most importantly, your health. We’ll also revisit Florida, fishing, and introduce a special girl I met at Ave Maria University. removes estrogenic chemicals, fluoride, pesticides, herbicides, plastic chemicals, pharmaceuticals, and heavy metals ) Shortly after I met Dave and a few other new college classmates, we were all herded into a large auditorium. Lectures and orientation breakout sessions commenced. Electrolytes: A few years ago, all you could find for electrolyte pills/powders was salt with sugar. To make matters worse, the salt often was industrially processed crap with aluminum (a neurotoxin) or sea salt containing microplastics galore. Yet, for keto diets and heavy/long sweat sessions, good quality electrolyte complexes are tremendously important. They'll prevent cramps and nausea. They prevent or at least help with "keto flu". For pills, I like Hi Lyte, LINK. More recently, I've moved away from pills and started using electrolyte powders simply because they taste amazing. I love Robb Wolf's LMNT electrolyte powders and he has many excellent flavors LINK. I also love Clovis Hydration Drink Mix, LINK. Be aware if you are super sensitive to heart palpitations, the potassium in all of these may be an issue for you.

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I hesitate to include supplements here because there is no "one-size-fits-all" supplement plan. Your DNA, sex, age, health history, current diet, personal goals, and your body's responses all determine what supplements you should utilize. That’s one reason I do DNA consultingand believe it's incredibly empowering. Melatonin: I know people that go up to 100 mg per day with their melatonin dose. If you decide to try high doses like that, don't start high. I've also seen many cases where melatonin increases REM but decreases deep sleep, so watch for that when you use it. For high dosages, I use Bulk Supplements, LINK, and the supplement scale (listed above) to save money if you use it long term. Otherwise, for a more standard dose, go with Puritan’s Pride Super Strength, Rapid Release, 10 mg, LINK, and don't hesitate to use half a pill or less to start. Manson JE, Aragaki AK, Rossouw JE, et al. Menopausal Hormone Therapy and Long-Term All-Cause and Cause-Specific Mortality. JAMA. September 12, 2017. L-Theanine: A number of people like L-theanine for sleep, taken before bed. Purity is important and that's why Thorne is excellent here, LINK When this happens, your doctor may recommend taking prescription estrogen to help with severe menopausal symptoms, such as:

Chromium: For that sweet tooth gene variant and problems with overwhelming sugar cravings, use Pure Encapsulations, 500 micrograms, LINK Mono-Species: Swanson L. Plantarum Probiotic [Lactobacillus plantarum are useful for degrading histamines and tyramines ( ref)] LINK Multivitamin: You don't need a full multivitamin. Eat egg yolks. If for some reason, you still want a multi, my favorite multi is Designs for Health (DFH) Primal Multivitamin, LINKFat being the largest organ is contrary to what most people think. For example, here is a scene from the TV show, The Office: Mono-Species: Life Extension, Bifido Gi Balance [ Bifidobacterium longum is another probiotic to try if you have histamine issues and a high number of food sensitivities ( ref)] LINK

Concerns about hormone replacement therapy (HRT) began in the early 2000s, when the Women’s Health Initiative (WHI) study reported a link between combined estrogen and progestin and an increased risk of breast cancer and cardiovascular disease. The study also stated that hormone therapy caused more harm than good in postmenopausal women, showing that estrogen alone appeared to be related to an increased risk of stroke and was not beneficial for coronary artery disease. ( 4) DARLENE: So we really appreciate, listeners, we really appreciate you sharing your comments with us because you know what? Honestly, we spend a lot of time putting this show together. L-Methionine: If you have a genetic issue making methionine, this one's for you. Try taking at least 1,000 mg per day, NOW Foods, LINKDARLENE: Right. So I think that Anthony Jay, you know, who wrote this wonderful book: it's going to help clear up some misunderstanding or even get us to understand how these artificial toxic estrogens, what they are and where they come from and what damage that they actually can do to your body. So we are really pleased that you drove off from Rochester. I actually grew up around Rochester, so I grew up in a little town outside of Rochester, so I know that place well. But before spending money on the perfect filter or making a single lifestyle change, you really need to be convinced that there is a problem. Not only that, but you also need to be convinced that the problem is immense. That’s my job. You won’t endure open heart surgery if you believe you are perfectly healthy, as I explain to my high-school religious ed students in Boston. Recognition of a major problem is necessary to motivate a major—and oftentimes inconvenient—change. Mono-Species: Align Probiotics for Digestive Health [“Bifidobacterium 35624” has proven to be beneficial for some people with IBS ( ref) and the related Bifidobacterium infantis helps your gut clear histamine ( ref)], LINK In business, Dr. Jay has been the President of theInternational Medical Research Collaborative(IMRCo), a non-profit organization that provided training to international medical students and doctors. Dr. Jay is also the CEO of the AJ Consulting Company, which specializes in scientific consulting, speaking, and personalized DNA analysis. So, at 3 A.M. that very night, we all drove over to the Naples Wal-Mart and bought a chrome water filter and a yellow whiffle ball bat. I never understood why we bought the whiffle ball bat but the water filter saw heavy use.