Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch. Call your doctor if your symptoms do not improve after 3 days of treatment, or if you have a fever with a headache, cough, or skin rash.

People who have taken the medicines phenelzine, isocarboxazid, tranylcypromine, rasagiline, selegiline or safinamide in the last 14 days. As this nasal spray causes the blood vessels in the nose to contract, it minimises the amount of medicine that is absorbed into the bloodstream from the nose. This means that the nasal spray has a relatively local effect in the nose and side effects on other parts of the body are extremely unlikely. Do not give Sinex Nasal Spray to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. severe sneezing, runny or stuffy nose, redness or swelling in your nose, or other worsening nasal symptoms (may be a sign of overuse of Sinex Nasal Spray);Oxymetazoline HCI 0.05% w/v (active ingredient), Sorbitol, Sodium Citrate Dihydrate, Tyloxapol, Chlorhexidine Digluconate Soultion, Citric Acid Anhydrous, Benalkonium Chloride Solution, Acesulfame Potassium, Menthol (Levo), Cineole, Disodium Edetate (Dihydrate), Aloes Dry Extract, Carvone (Levo), Sodium Hydroxide, Purified Water. Adults and children aged 12 years and over should use one to two sprays in each nostril two to three times a day as needed. If you have taken certain drugs for depression or Parkinson's disease in the last 14 days. This includes isocarboxazid, phenelzine, Please inform your doctor before use if you are taking tricyclic antidepressants or Bethanidine, Debrisoquine and Guanethidine (medicines used in the treatment of high blood pressure). Brand names: 12 Hour Decongestant, 12 Hour Nasal Decongestant, 12 Hour Nasal Relief Spray, 12 Hour Nasal Spray, Afrin 12 Hour,

Are allergic (hypersensitive) to active substance oxymetazoline hydrochloride or any other listed ingredients.Sinex Nasal Spray may cause serious side effects. Stop using Sinex Nasal Spray and call your doctor at once if you have: For reasons of hygiene, don't use the nasal spray if it has been more than 28 days since you first opened it.

Are taking (or have taken during the last 2 weeks) monoamine oxidase inhibitors (IMAO inhibitors are used in the treatment of Parkinsons disease and depression). As with all medicines, please inform your doctor or pharmacist if you are taking or have recently taken any other medicines, even those not prescribed. Some of these drugs need to be shaken before use. Be sure you know if this product needs to be shaken before using it.

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After each use, clean the tip of the spray bottle with a clean tissue or rinse it with hot water, making sure that no water gets into the medicine bottle. Keep the cap on the bottle when not in use.